Cell membrane electroporation-Part 2: the applications
نویسندگان
چکیده
منابع مشابه
The Pulse Intensity - duration dependency for Cell Membrane Electroporation
External electric field, which is applied to cells, can, under suitable field parameters, induce local distortions and structural rearrangements of lipid molecules in the cell membrane. Depending on the field parameters, the membrane hence becomes either transiently or permanently permeable even after the field has ceased, allowing molecules that are otherwise deprived of transport mechanisms t...
متن کاملStudies on the SPEEK membrane with low degree of sulfonation as a stable proton exchange membrane for fuel cell applications
Sulfonated poly (ether ether ketone) (SPEEK) with a low degree of sulfonation (DS = 40%) was prepared for proton exchange membrane fuel cells (PEMFC). Poly (ether ether ketone) (PEEK) was sulfonated in concentrated H2SO4 under N2 atmosphere and characterized by the hydrogen nuclear magnetic resonance (H-NMR) technique. After preparation of the SPEEK polymer, the obtained polymer was dissolved i...
متن کاملResealing dynamics of a cell membrane after electroporation.
The membrane of a living cell consists of a bilayer of amphipolar lipid molecules as well as much larger proteins. Transmembrane potentials of up to 120 mV are physiologic and well tolerated, but when the potential is more than 300 mV, this lipid bilayer is unstable. Pores are then formed through which measurable flow of ions can occur. We follow currents through frog muscle cell membranes unde...
متن کاملSimulation of Normal and Cancerous T-cell Membrane Electroporation
Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field [1][2]. The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs into the cell in a cancer treatment known as electrochemotherapy [3]. In some cases the direct experimental me...
متن کاملModel of Cell Membrane Electroporation and Transmembrane Molecular Transport
Electroporation is a technique in which, under the influence of electric field, the permeability of the cell membrane increases due to the formation of pores in the cell membrane, providing pathways for molecular transport (Abidor et al. 1979, Neumann et al. 1998, Tsong 1991, Weaver and Chizmadzhev 1989, Zimmermann 1982). As electroporation is usually evaluated by indirect indications (Gehl and...
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ژورنال
عنوان ژورنال: IEEE Electrical Insulation Magazine
سال: 2013
ISSN: 0883-7554
DOI: 10.1109/mei.2013.6410537